Panta Rhei Study Group is an international group of multidisciplinary physicians and researchers dedicated to elucidate the pivotal role of angiogenesis in health and disease. We could show the important impact of different forms  of blood vessel new formation in development, tissue regeneration, fibrosis, inflammation, and cancer.

Since the  COVID-19 pandemic has become a global threatening challenge for global health care and social systems, our dedicated mission is to decipher and understand the mechanisms and injury patterns induced by SARS-CoV2-infection in many organs.   

Maximilian Ackermann, MD

Institute of Functional and Clinical Anatomy, University Medical Center, Johannes Gutenberg-University Mainz, Germany

Institute of Pathology and Molecular Pathology, Helios University Clinic Wuppertal, Germany


Danny Jonigk, MD

Institute of Pathology, Hannover Medical School, Hanover,  Germany

German Center for Lung Research (DZL), Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH)

Steven J. Mentzer, MD

Division of Thoracic Surgery, Brigham & Women’s Hospital, Harvard Medical School, Boston, USA

Laboratory of Adaptive and Regenerative Biology, Harvard Medical School, Brigham & Women's Hospital,Boston, USA


Research topics

We are focusing on the impact of angiogenesis in the following organs:





Mainz & Wuppertal Group

Hannover Group

Leuven Group

Drs. Verleden and Vanstapel are expert in µCT-based imaging of lung diseases. They are members of the Laboratory of Respiratory Diseases, BREATH, Department of CHROMETA, KU Leuven, Leuven, Belgium

Stijn Verleden, PhD

Arno Vanstapel, MD

The Angiogenesis Foundation

The Angiogenesis Foundation is the leading nonprofit organization disrupting disease through angiogenesis, the process the body uses to grow new blood vessels. 

William W. Li, MD

Vincent W. Li, MD MBA

Covid-19 Synchrotron Moonshot

Synchrotron radiation-based computer tomography is a X-ray imaging technique allowing structural analysis on a micro- and nanolevel. Synchrotron-based radiation is 10,000 billion more powerful than X-rays used in the medical field.

Professor Peter Lee and Dr. Paul Tafforeau are pioneering experts in Synchrotron-based computer tomography and joined the Panta Rhei Study Group by analyzing the morphological and structural changes of SARS-CoV-2 infection in different organs on ultra-high resoultion level.

Peter D.  Lee, PhD

University College London, UK / Imperial College, UK

Diamond Light Source, Oxford, UK

Professor Lee is an international pioneering expert on multiscale imaging and microstructural analysis using Synchrotron radiation-based µCT.

Paul Tafforeau, PhD

European Synchrotron Radiation Facility, Grenoble, France

Dr. Tafforeau is one of world's foremost paleontologist and Synchrotron expert characterizing micro- and nanostructures.

Diamond Light Source

Harwell Science and Innovation Campus, Oxfordshire, UK

Diamond Light Source (DLS) is UK's national synchrotron light source operating seven beamlines focusing on nanoscience, microfocus spectroscopy, macromolecular crystallography, extreme condition beamlines.

DLS is a world-known research institution for material science, protein crystallography and biosciences.


European Synchrotron Radiation Facility (ERSF)

Grenoble, France

European joint Synchrotron particle accelerator with fourth generation synchtrotron in the world

ERSF focuses on the use of X-ray radiation in diverse fields (material sciences, physics, protein crystallography etc.)

Claire Walsh, PhD

University College London, UK

Willi Wagner, MD

University Heidelberg, Germany

Andrew Bodey, PhD

Diamond Light Source, UK

Christopher Rau, PhD

Diamond Light Source, UK

Elodie Boller, PhD

European Synchrotron Radiation Facility (ERSF), France


© 2020 Maximilian Ackermann. All rights preserved.